We firmly believe that the best way to find a cure for neuromuscular disorders is through collaboration, innovative research, and a rigorous adherence to scientific principles. We offer different programs and funding opportunities to support research.
We currently offer research funding through:
Grants
Year | Lead Investigator | Affilliation, Lead Investigator | Name of Project | Grant Program | Disorder Keywords |
---|---|---|---|---|---|
2020 - 2022 | Dr. Luc Hébert | Université Laval, QU | Muscle strength reference values for adults: a critical need in NMD | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2019/2020 to 2022/2023 | Dr. Hans Lochmuller | National | NMD4C: An integrated research network for patients, scientists, and clinicians to improve outcomes and access to therapies for patients with neuromuscular disorders in Canada | CIHR Partnership - Network Catalyst Grant | Neuromuscular Disorders |
2020 - 2023 | Dr. Michael Rudnicki | Ottawa Hospital Research Institute, ON | A multidimensional single-cell approach to understand muscle dystrophy | CIHR Partnership - EJPRD | Duchenne Muscular Dystrophy, LAMA2-related Muscular Dystrophy |
2020 - 2022 | Dr. Reshma Amin | The Hospital for Sick Children, ON | A Virtual Transition Intervention For Children and Adults Transitioning To Home Ventilation in Ontario: A Pragmatic Randomized Controlled Tria | CIHR Partnership- Team Grant Transitions in care gaps | Neuromuscular Disorders |
2020 - 2022 | Dr. Martine Tétreault | Centre Hospitalier de l'Université de Montréal, QU | Identification of modifiers underlying the variable phenotypes of RYR1 myopathy | MDC Annual Research Grant Competition | Congenital Myopathy; RYR1 myopathy |
2020 - 2022 | Dr. Rashmi Kothary | Ottawa Hospital Research Institute, ON | Canonical disease features in a novel mouse model of SMA type III and IV | MDC Annual Research Grant Competition | Spinal Muscular Atrophy |
2020 - 2022 | Dr. Vladimir Ljubicic | McMaster University, ON | Reverse translation from the diabetes clinic to pre-clinical muscular dystrophy | MDC Annual Research Grant Competition | Myotonic Dystrophy; Duchenne Muscular Dystrophy |
2020 - 2022 | Dr. Benjamin Gallais | Cégep de Jonquière, QU | Empowering caregivers to better manage DM patients' neurobehavioral symptoms | MDC Annual Research Grant Competition | Myotonic Dystrophy |
2020 - 2022 | Dr. Benoit Gentil | The Royal Institution for the Advancement of Learning/ McGill University, QU | Therapeutic potential of CK1 agonists in inherited peripheral neuropathies | MDC Annual Research Grant Competition | Hereditary motor and sensory neuropathies, Charcot-Marie-tooth disease, rare ataxia |
2020 - 2022 | Dr. Carolina Barnett-Tapia | University Health Network, ON | Patient preferences in treatments for myasthenia gravis: a DCE experiment | MDC Annual Research Grant Competition | Myasthenia Gravis |
2020 - 2022 | Dr. David Granville | University of British Columbia, BC | Profiling granzymes in inflammatory neuromuscular diseases | MDC Annual Research Grant Competition | Inflammatory myopathy; (Myositis; Polymositis, dermatomyositis; inclusion-body myositis); Chronic inflammatory demyelinating polyneuropathy; Myasthenia gravis |
2020 - 2022 | Dr. James Dowling | The Hospital for Sick Children, ON | CRISPR mediated gene editing: a novel therapeutic strategy for nemaline myopathy | MDC Annual Research Grant Competition | Congenital Myopathy; Nemaline myopathy |
2018 - 2020 | Dr. Gerald Pfeffer | University of Calgary, AB | Interventional Study of Expiratory Muscle Strength Training as a Treatment for Muscle Disease” | MDC Annual Research Grant Competition | Myopathy (hereditary) |
2018 - 2020 | Dr. Leanne M. Ward | Children's Hospital of Eastern Ontario, ON | Denosumab for the Treatment of Osteoporosis in Boys with Duchenne Muscular Dystrophy: A Pilot Study | MDC Annual Research Grant Competition | Duchenne Muscular Dystrophy |
2018 - 2019 | Dr. Ari Breiner | Ottawa Hospital, ON | A Population-based Cohort Study of Pregnancy Outcomes in Women with Myasthenia Gravis | MDC Annual Research Grant Competition | Myasthenia Gravis |
2018 - 2019 | Dr. Cynthia Gagnon | École de réadaptation CIUSSS du Saguenay—Lac-St-Jean, QU | A better trunk and lower limb control for a better mobility: Assessment of a re-entrainment program in Autosomal recessive spastic ataxia of Charlevoix-Saguenay | MDC Annual Research Grant Competition | Autosomal recessive spastic ataxia of Charlevoix-Saguenay |
2018 - 2019 | Dr. Cynthia Gagnon | École de réadaptation CIUSSS du Saguenay—Lac-St-Jean, QU | Quand attendre est synonyme de meilleurs services : Création d'une salle d'attente interactive pour informer les personnes atteintes de maladies neuromusculaires des enjeux de la recherche | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2018 - 2019 | Laura Oldford, Lise Bleau | Stan Cassidy Centre for Rehabilitation, NB | Exploring the impact of simple robotic assistive technology on the quality of life of individuals with neuromuscular disease | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2017 - 2019 | Dr. Ellen Roche | Massachusetts Institute of Technology, USA | Development of a Soft Robotic Diaphragmatic Assist Device for Diaphragm Dysfunction in Muscular Dystrophy | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2017 - 2018 | Dr. Reshma Amin | The Hospital for Sick Children, ON | The Diagnostic Accuracy and Reliability of Transcutaneous Carbon Dioxide Monitoring at Home for Nocturnal Hypoventilation Screening in Children with Neuromuscular Disease | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2017 - 2018 | Dr. Cynthia Gagnon | École de réadaptation CIUSSS du Saguenay—Lac-St-Jean, ON | Development of a Questionnaire to Assess the Severity of Dysphagia in Neuromuscular Disorders: a pilot study | MDC Annual Research Grant Competition | Myotonic Dystrophy, Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay |
2017 - 2018 | Dr. Unni Narayanan | The Hospital for Sick Children, ON | Validation of the Muscular Dystrophy Child Health Index of Life with Disabilities (MDCHILD) Questionnaire in children with other chronic neuromuscular conditions | MDC Annual Research Grant Competition | Pediatric Neuromuscular Disorders |
2017 - 2018 | Dr. Danielle Peers | University of Alberta, AB | Moving to Breathe, Breathing to Move: An interdisciplinary study on the benefits of choral and dance exercise for people with neuromuscular conditions | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2017 - 2018 | Dr. Jodi Warman Chardon | The Ottawa Hospital, ON | Diagnostic Utility of Muscle MR Imaging in Genetic Myopathies | MDC Annual Research Grant Competition | Myopathy (hereditary) |
2015 - 2016 | Dr. Christine Vande Velde | University of Montréal | Cell biological mechanisms of TDP-43 in ALS | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2012 - 2017 | Dr. Sanjay Kalra | University of Alberta | Magnetic resonance imaging biomarkers in ALS | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2012 - 2017 | Dr. Bernard Jasmin | University of Ottawa | Post-transcriptional Regulation of Utrophin in Skeletal Muscle: Implications for New Therapeutic Strategies for Duchenne Muscular Dystrophy | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Duchenne Muscular Dystrophy |
2012 - 2017 | Dr. Marc Grynpas | Mount Sinai Hospital, Toronto | Growth arrest and osteoporosis in Duchenne muscular dystrophy patients treated with glucocorticoids | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Duchenne Muscular Dystrophy |
2012 - 2017 | Dr. Stephano Stifani | McGill University | Regulation of motor neuron identity and circuit development | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Motor Neuron Disorders |
2012 - 2017 | Dr. Stephano Stifani | McGill University | Regeneration of motor neurons controlling movement and respiration from embryonic stem cells | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Motor Neuron Disorders; Spinal Muscular Atrophy; Amyotrophic Lateral Sclerosis |
2012 - 2017 | Dr. Michael A Rudnicki | Ottawa Hospital Research Institute, ON | Genetic Regulation of Myogenesis | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Duchenne Muscular Dystrophy |
2012 - 2016 | Dr. Panayiotis Vacratsis | University of Windsor | Molecular mechanisms regulating the myotubularin-related 2 lipid phosphatases mutated in the neuromuscular disorder Charcot-Marie-Tooth disease | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Charcot-MarieTooth disease |
2012 - 2015 | Dr. Anthony Gramolini | University of Toronto, ON | Molecular basis of ryanodine receptor regulation and function in skeletal and cardiac muscle | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Congenital myopathy; RYR related disorders (central core disease, centronuclear myopathy, multiminicore disease, congenital fiber-type disproportion) |
2012 - 2015 | Dr. Jérôme Frenette | Université Laval, QU | Rank/Rankl/OPG: a new pathway that regulates skeletal muscle disuse, aging and disease | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Neuromuscular Disorders |
2012 - 2015 | Dr. Neil Cashman | University of British Columbia | Misfolding of Cu/Zn superoxide dismutase by pathological FUS and TDP43: relevance to ALS | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2012 - 2015 | Drs. Robin Michel & Bernard Jasmin | Concordia University /Université Concordia, QU | Identifying novel roles of calcineurin signaling in the control of multiple complementary pathways affecting the dystrophic phenotype | Duchenne Muscular Dystrophy | |
2012 - 2015 | Dr. Jacques Tremblay | Université Laval | Correction of the dystrophin gene with Zinc Finger Proteins and TAL effector nuclease | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Duchenne Muscular Dystrophy |
2012 - 2015 | Dr. Jacques Tremblay | Université Laval | Inhibition of myostatin receptor expression to improve MPC transplantation | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Duchenne Muscular Dystrophy |
2012 - 2014 | Dr. Jack Puymirat/ Dr. Matthew Wood | Université Laval/ University of Oxford | Evaluation of peptide antisense oligonucleotides as gene therapy for myotonic dystrophy | MDC; The Rachel Fund, The French Muscular Dystrophy Association | Myotonic Muscular Dystrophy |
2011 - 2016 | Dr. Michael A Rudnicki | Ottawa Hospital Research Institute, ON | Satellite Stem Cells from Skeletal Muscle for the Treatment of Neuromuscular Disease | Muscular Dystrophy Canada Grant | Muscular Dystrophy |
2011 - 2016 | Dr. Hiroshi Tsuda | Montreal Neurological Institute | Studies on the Molecular Pathogenesis of Amyotrophic Lateral Sclerosis | Muscular Dystrophy Canada Grant | Amyotrophic Lateral Sclerosis |
2011 - 2016 | Dr. Basil Petrof | (The Research Institute of McGill University Health Center) | Strategies for Therapy of Respiratory Muscle Failure in Muscular Dystrophy | Muscular Dystrophy Canada Grant | Duchenne Muscular Dystrophy |
2011 - 2016 | Dr. Jean-Marc E Renaud | University of Ottawa/Université d'Ottawa, ON | Development of Better and More Effective Treatment for Patients Suffering from Hyperkalemic Periodic Paralysis (HyperKPP) (2011-2016) | Hyper-kalemic Periodic Paralysis | |
2011 - 2014 | Dr. Alexander E Mackenzie | Children's Hospital of Eastern Ontario Research Institute, ON | Preclinical assessment of clinic ready agents for the treatment of muscular dystrophy and spinal muscular atrophy | Muscular Dystrophy Canada Grant | Myotonic Muscular Dystrophy, Spinal Muscular Atrophy |
2011 - 2014 | Dr. Douglas Ashley Monks | University of Toronto, ON | Mouse models of Kennedy Disease/Spinobulbar Muscular Atrophy | CIHR Partnership: Operating Grant - Priority Announcement: Neuromuscular Research | Spinobulbar Muscular Atrophy (Kennedy Disease) |
2011 - 2014 | Dr. Thomas Hawke | McMaster University, ON | Role of Xin, an actin-binding protein, in satellite cells and muscular dystrophies | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Muscular Dystrophy |
2011 - 2014 | Dr. Jasna Kriz | Université Laval | Glia-Neuron Crosstalk in Early Amyotrophic Lateral Sclerosis Pathogenesis | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2011 - 2014 | Dr. Janice Robertson | University of Toronto, ON | The TAR-DNA-binding protein-43 and amyotrophic lateral sclerosis | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2010 - 2015 | Dr. Serge Rivest | Université Laval | Therapeutic properties of the innate immune response by microglia | Amyotrophic Lateral Sclerosis | |
2010 - 2015 | Dr. Josephine Nalbantoglu | McGill University, QU | Artificial zinc finger transcription factors targeting the utrophin promoter as a potential therapy for Duchenne muscular dystrophy | Duchenne Muscular Dystrophy | |
2010 - 2015 | Dr. Jeffrey Dilworth | Ottawa Hospital Research Institute, ON | Differential role of myogenic regulatory factors in establishing muscle-specific gene expression | Muscular Dystrophy | |
2010 - 2015 | Dr. François Bachand | Université de Sherbrooke, QU | Characterization of a novel function for PABPN1:the product ofthe oculopharyngeal muscular dystrophy disease gene | Oculopharyngeal muscular dystrophy | |
2010 - 2013 | Dr. Jean-Pierre Julien | Université Laval, QU | Pathogenic mechanisms associated with neurofilament disorganization | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2010 - 2013 | Dr. Kelvin E Jones | University of Alberta, AB | Promoting protection of functionally intact motor units in amyotrophic lateral sclerosis (ALS). | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2010 - 2013 | Dr. Victor Rafuse | Dalhousie University, NS | Developing specific motoneuron subtypes from embryonic stem cells, and induced pluripotent stem cells, to treat neuromuscular disorders and paralysis due to injury. | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | |
2009 - 2014 | Dr. Guy A Rouleau | Centre hospitalier de l'Université de Montréal (CHUM), QU | Mutation of KCC3: Understanding a sensory motor neuropathy | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2009-2014 | Dr. Charles Krieger | Simon Fraser University, BC | Bone Marrow-Derived Cells as Gene Delivery Vehicles in Amyotrophic Lateral Sclerosis (ALS) | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2009 - 2014 | Dr. Janice Robertson | University of Toronto, ON | Peripherin Abnormalities in Amyotrophic Lateral Sclerosis | CIHR Partnership: Operating Grant - Priority Announcement: Neuromuscular Research | Amyotrophic Lateral Sclerosis |
2009 - 2014 | Dr. Blair R Leavitt | Centre for Molecular Medicine & Therapeutics, BC | Determination of muscle properties that alter ALS onset and disease progression using the G93A mouse model of ALS | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Amyotrophic Lateral Sclerosis |
2009 - 2012 | Dr. Christopher Pearson | Hospital for Sick Children, ON | Genetic modifiers of CTG trinucleotide repeat instability and myotonic dystrophy pathogenesis | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Myotonic Muscular Dystrophy |
2009 - 2012 | Dr. Basil Petrof | (The Research Institute of McGill University Health Center) | Mitochondrial function as a therapeutic target in muscular dystrophy | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Duchenne Muscular Dystrophy |
2008 - 2013 | Dr. Guy A Rouleau | Centre hospitalier de l'Université de Montréal (CHUM), QU | Cellular and biochemical impact of TDP-43 mutants in ALS | Amyotrophic Lateral Sclerosis | |
2018 | Dr. Anthony Gramolini | University of Toronto, ON | Non-viral, immune-modulatory nanoparticles for delivery of CRISPR/Cas9 as a treatment intervention for Duchenne Muscular Dystrophy. | Jesse Journey Partnership | Duchenne Muscular Dystrophy |
2018 | Dr. Michael A. Rudnicki | Ottawa Hospital Research Institute, ON | Exosomal Delivery of Wnt7a for treating Duchenne Muscular Dystrophy. | Jesse Journey Partnership | Duchenne Muscular Dystrophy |
2017 | Dowling, James | The Hospital for Sick Children, ON | Novel therapies for neuromuscular diseases with altered phosphoinositide metabolism | Team Grant: Transnational Research Projects on Rare Diseases | Congenital Myopathies |
2016 | Dr. Amy McPherson | Bloorview Research Institute, ON | Promoting healthy weights to support respiratory function in children with Duchenne muscular dystrophy | MDC Annual Research Grant Competition | Duchenne Muscular Dystrophy |
2016 | Dr. Louise Rose | Sunnybrook Research Institute, ON | Development & Pilot Evaluation of an Online Peer Support Program for Family Caregivers of Ventilator-Assisted Individuals with Neuromuscular Disease Living in the Community | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2016 | Dr. Sherri Katz | Children's Hospital of Eastern Ontario, ON | Understanding the Acceptability of Lung Volume Recruitment Among Boys with Duchenne Muscular Dystrophy: A Mixed- Methods Sub-study of the STEADFAST Trial | MDC Annual Research Grant Competition | Duchenne Muscular Dystrophy |
2015 | Dr. Hans Katzberg | University Health Network/University of Toronto, ON | Clinical Determinants of Nocturnal Hypoventilation in Patients with Adult and Pediatric Myasthenis Gravis | MDC Annual Research Grant Competition | Myasthenis Gravis |
2015 | Dr. Marta Kaminska | McGill University, QU | Validation of home portable monitoring for diagnosis of sleep disordered breathing in adolescents and adults with neuromuscular disorders | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2015 | Dr. Louise Rose | Sunnybrook Research Institute, ON | Translating Recommendations for Airway Clearance from the Canadian Thoracic Society Home Mechanical Ventilation | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2015 | Dr. Reshma Amin | The Hospital for Sick Children, ON | Assessing Air Travel Safety in Duchenne Muscular Dystrophy: Standard versus Prolonged High Altitude Simulation Tests | MDC Annual Research Grant Competition | Duchenne Muscular Dystrophy |
2015 | Dr. Bernard Brais | Montreal Neurological Institute, QU | PREPARE: Preparing for therapies in autosomal recessive ataxias | Team Grant: Transnational Research Projects on Rare Diseases | Autosomal recessive ataxias |
2014 | Dr. Lawrence Korngut | National | Canadian Neuromusclar Network | CIHR Partnership: Network catalyst grant | Neuromuscular Disorders |
2014 | Dr. Craig Campbell | London Health Sciences Centre, ON | Understanding Decision Needs for Respiratory interventions in Pediatric Neuromuscular Disorders: Laying the Foundation for Developing a Shared Decision Environment for Respiratory Care Decisions | MDC Annual Research Grant Competition | Pediatric Neuromuscular Disorders |
2014 | Dr. Judy King | Ottawa Hospital, ON | A respiratory-focused e-learning resource for people living with neuromuscular disease and their families | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2014 | Dr. Louise Rose | Sunnybrook Research Institute, ON | Health Service Utilization for Assessment, Monitoring and Management of Respiratory Complications for Individuals with Neuromuscular Disease | MDC Annual Research Grant Competition | Neuromuscular Disorders |
2014 | Dr. Michael Seear | University of British Columbia, BC | Comparison of three methods for improving expiratory cough flow and lung volume in children with neuromuscular disease | MDC Annual Research Grant Competition | Pediatric Neuromuscular Disorders |
2013 | Dr. F J Dilworth | Ottawa Hospital Research Institute, ON | An international effort to understand FSHD muscular dystrophy epigenetics | CIHR & European Rare Network Partnership: Operating Grant - E-Rare-2 Joint Transnational Call on Rare Diseases | Facioscapulohumeral muscular dystrophy |
2013 | Dr. Michael A Rudnicki | Ottawa Hospital Research Institute, ON | Stimulating Intrinsic Repair for DMD (SIRD) | CIHR & European Rare Network Partnership: Operating Grant - E-Rare-2 Joint Transnational Call on Rare Diseases | Duchenne Muscular Dystrophy |
2011 | Dr. Toshifumi Yokota | University of Alberta | The Friends of Garrett Cumming Research Chair, Muscular Dystrophy Canada | MDC, University of Alberta, Government of Alberta's Access to the Future Fund | Duchenne Muscular Dystrophy |
2011 | Dr. Robin N Michel | Concordia University /Université Concordia, QU | Role of calcineurin and its signaling modulators in the dystrophic phenotype | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | |
2010 | Dr. Elizabeth Meiering | University of Waterloo, ON | Folding and aggregation of ALS-associated mutant superoxide dismutases | Amyotrophic Lateral Sclerosis | |
2010 | Drs. Jean Mathieu, Cynthia Gagnon | Hôpital de Jonquière, QU | Motor, multisystemic and social participation assessment in myotonic dystrophy type 1: a 9-year longitudinal study. | MDC, CIHR & ALS Canada Neuromuscular Research Partnership | Myotonic Dystrophy |
2008 | Dr. Jane Andrea E Batt | University of Toronto, ON | Nedd4 Regulation of Skeletal Muscle Atrophy and Regeneration | Operating Grant - Priority Announcement: Neuromuscular Research | |
2008 | Dr. Bernard Brais | Centre hospitalier de l'Université de Montréal (CHUM), QU | Developing molecular, cellular and mice models for Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) | CIHR Operating Grant - Priority Announcement: Neuromuscular Research | Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay |
2008 | Dr. Jean-Marc E Renaud | University of Ottawa/Université d'Ottawa, ON | Mutation of the mouse nav1.4 muscle sodium channel: understanding hyperkalemic periodic paralysis (hyperkpp) | Operating Grant - Priority Announcement: Neuromuscular Research |